ABSTRACT

Objective:

Erectile dysfunction (ED) is quite common in men with severe Obstructive Sleep Apnea syndrome (OSAS). The aim of this study was to determine whether a hematological parameter can be used for predicting ED in male patients with OSAS

Materials and Methods:

Patients who applied to neurology-sleep disorders outpatient clinic of our hospital between March of 2018 and 2020, who had Apnea-hypopnea index ≥30 in polysomnography test, and who met the inclusion criteria were enrolled in this study. The patients were divided into two groups as those without ED (group 1) and with ED (group 2) according to the score of International Erectile Function (IIEF) questionnaire. The recorded demographic and basic characteristics of the patients along with measured hemogram, fasting serum biochemistry, blood lipid profile, and serum sex hormone parameters were statistically analyzed.

Results:

Of the 85 patients enrolled in the study, 48 (56.5%) had ED. While average age of all patients was 47.43±10.73 years, it was 43.95±8.70 years in group 1 and 49.96±11.06 years in group 2 and differed significantly between the two groups (p=0.006). Mean hemoglobin and hematocrit values in group 1 were higher than those in group 2 (p=0.02 and p=0.03, respectively). Other parameters were similar among the groups. In multivariate logistic regression analysis, only patient age remained significantly different (p=0.011). Pearson correlation analysis revealed a negative relationship between patient age and IIEF score (r =-0.287, p=0.004). In receiver operating characteristic analysis, cut-off value of the patient age was found to be 47.50 years with a sensitivity of 0.604 and a specificity of 0.646 (p=0.006).

Conclusion:

The results suggest that prevalence of ED increases in parallel with age in men with severe OSAS. No hematological, hormonal, or biochemical parameters for predicting ED have yet been determined.

Keywords: Erectile dysfunction, Obstructive Sleep Apnea syndrome, Predictor, Aging

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Is There Any Hematological Parameter Predicting Erectile Dysfunction in Male Patients with Severe Obstructive Sleep Apnea Syndrome?

ABSTRACT

References