The Relationship of Dry Eye Disease with Depressive Symptom Scores and Insomnia
PDF
Cite
Share
Request
Original Article
P: 49-52
June 2019

The Relationship of Dry Eye Disease with Depressive Symptom Scores and Insomnia

J Turk Sleep Med 2019;6(2):49-52
1. Ahi Evran Üniversitesi Eğitim ve Araştırma Hastanesi, Çocuk ve Ergen Ruh Sağlığı ve Hastalıkları Anabilim Dalı, Kırşehir, Türkiye
2. Ahi Evran Üniversitesi Tıp Fakültesi, Göz Hastalıkları Anabilim Dalı, Kırşehir, Türkiye
No information available.
No information available
Accepted Date: 09.04.2019
Publish Date: 31.05.2019
PDF
Cite
Share
Request

ABSTRACT

Objective:

The aim of this study was to investigate whether there is a difference in terms of depressive symptom and insomnia scores between patients with dry eye disease and healthy controls.

Materials and Methods:

Forty patients who applied to ophthalmology outpatient clinic with dry eye symptoms and had no history of chronic disease or drug use and who were diagnosed with dry eye for the first time in our clinic, and 34 healthy controls were included in the study. Beck Depression Inventory in order to evaluate the depressive symptom scores and the Insomnia Severity Index scores for the severity of insomnia were analyzed. Independent samples t-test was used to determine whether there was any difference between the groups.

Results:

The depressive symptom score was 14.5±6.8 and insomnia severity score was 13.4±5.2 in individuals with dry eye disease; while depressive symptom and insomnia severity scores in the control group were 5.5±1.8 and 4.5±2.2, respectively. The difference between the groups was statistically significant (p=0.001).

Conclusion:

It is thought that revealing the relationship between dry eye disease and depressive symptoms and insomnia is important in understanding the pathophysiology of these diseases, as well as the multisystemic approach including evaluation of comorbid psychological/ psychiatric conditions besides the objective symptoms of the disease, will have a positive effect on the quality of life of individuals.

Keywords: Dry eye, depression, insomnia

References

1
Craig JP, Nichols KK, Akpek EK, Caffery B, Dua HS, Joo CK, Liu Z, Nelson JD, Nichols JJ, Tsubota K, Stapleton F. TFOS DEWS II Definition and Classification Report. Ocul Surf 2017;15:276-83.
2
Smith JA. The epidemiology of dry eye disease. Acta Ophthalmologica Scandinavica 2007;85.
3
Hashemi H, Khabazkhoob M, Kheirkhah A, Emamian MH, Mehravaran S, Shariati M, Fotouhi A. Prevalence of dry eye syndrome in an adult population. Clin Exp Ophthalmol 2014;42:242-8.
4
Jie Y, Xu L, Wu YY, Jonas JB. Prevalence of dry eye among adult Chinese in the Beijing Eye Study. Eye (Lond) 2009;23:688-93.
5
Chen W, Li J, Zheng Q. Prevalence and Risk Factors of Dry Eye Disease Among a Hospital-based Population. Invest Ophthalmol Vis Sci 2013;54:935.
6
Miljanovc B, Dana R, Sullivan DA, Schaumberg DA. Impact of dry eye syndrome on vision-related quality of life. Am J Ophthalmol 2007;143:409-15.
7
Li M, Gong L, Chapin WJ, Zhu M. Assessment of vision-related quality of life in dry eye patients. Invest Ophthalmol Vis Sci 2012;53:5722-7.
8
Bergdahl M, Bergdahl J, Johansson I. Bergdahl, and I. Johansson, Depressive symptoms in individuals with idiopathic subjective dry mouth. J Oral Pathol Med 1997;26:448-50.
9
Tiskaoglu NS, Yazıcı A, Karlıdere T, Sari E, Oguz EY, Musaoglu M, Aslan S, Samet Ermiş S. Dry Eye Disease in Patients with Newly Diagnosed Depressive Disorder. Curr Eye Res 2017;42:672-76.
10
Galor A, Seiden BE, Park JJ, Feuer WJ, McClellan AL, Felix ER, Levitt RC, Sarantopoulos CD, Wallace DM. The Association of Dry Eye Symptom Severity and Comorbid Insomnia in US Veterans. Eye Contact Lens 2018;44:118-24.
11
Ayaki M, Kawashima M, Negishi K, Kishimoto T, Mimura M, Tsubota K. Sleep and mood disorders in dry eye disease and allied irritating ocular diseases. Sci Rep 2016;6:22480.
12
Beck At, Ward Ch, Mendelson M, Mock J, Erbaugh J. An inventory for measuring depression. Arch Gen Psychiatry 1961;4:561-71.
13
Hisli N. Beck Depresyon Envanterinin geçerliliği üzerine bir çalısma. Psikoloji Dergisi 1988;6:118-122.
14
Bastien CH, Vallières A, Morin CM. Validation of the Insomnia Severity Index as an outcome measure for insomnia research. Sleep Med 2001;2:297-307.
15
Boysan M, Güleç M, Beşiroğlu L, Kalafat T. Uykusuzluk Şiddeti İndeksi’nin Türk örneklemindeki psikometrik özellikleri. Anadolu Psikiyatri Dergisi 2010;11:248-52.
16
Uchino M, Schaumberg DA. Dry Eye Disease: Impact on Quality of Life and Vision. Curr Ophthalmol Rep 2013;1:51-7.
17
Labbé A, Wang YX, Jie Y, Baudouin C, Jonas JB, Xu L. Dry eye disease, dry eye symptoms and depression: the Beijing Eye Study. Br J Ophthalmol 2013;97:1399-403.
18
Wen W, Wu Y, Chen Y, Gong L, Li M, Chen X, Yan M, Xiao Z, Sun X. Dry eye disease in patients with depressive and anxiety disorders in Shanghai. Cornea 2012;31:686-92.
19
Ayaki M, Toda I, Tachi N, Negishi K, Tsubota K. Preliminary report of improved sleep quality in patients with dry eye disease after initiation of topical therapy. Neuropsychiatr Dis Treat 2016;12:329-37.
20
Sack RA, Beaton A, Sathe S, Morris C, Willcox M, Bogart B. Towards a closed eye model of the pre-ocular tear layer. Prog Retin Eye Res 2000;19:649-68.
21
Lee YB, Koh JW, Hyon JY, Wee WR, Kim JJ, Shin YJ. Sleep deprivation reduces tear secretion and impairs the tear film. Invest Ophthalmol Vis Sci 2014;55:3525-31.
22
Beebe DW. Cognitive, behavioral, and functional consequences of inadequate sleep in children and adolescents. Pediatr Clin North Am 2011;58:649-65.
23
Öztürk MO, Uluşahin A. Ruh sağlığı ve bozuklukları 2014. Ankara: Nobel Tıp Kitabevleri.
24
Önal GŞ, Hisar KM. Üniversite Öğrencilerinde Uykusuzluk Şiddeti ve Depresyon Semptomları İlişkisi ve Depresyon Tedavisinin Uykusuzluk Şiddetine Etkisi. Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi 2018:7;125-130.
2024 ©️ Galenos Publishing House