ABSTRACT

Objective:

Obsessive compulsive disorder (OCD) is one of the psychiatric disorders which causes labor loss and seen in between 1-2% of the society. The aim of this study is to compare OCD patients with healthy controls in terms of sleep quality and to investigate the relationship between sleep quality and clinical variables OCD patients.

Materials and Methods:

Forty-three OCD patients and forty healthy controls were included in the study. The Pittsburgh Sleep Quality index (PSQI), the Beck Depression inventory (BDI), the Beck Anxiety inventory (BAI), and the Yale-Brown obsessive compulsive scale (Y-BOCS) were applied to patients.

Results:

A significant difference determined between the OCD group and the control group in the mean scores of PSQI, BDI and BAI. There was also a significant difference in sleep quality between each two groups. A statistically significant difference was found between the PSQI total score and all the PSQI subscale scores of the OCD patient group and the control group. A relationship found between the Y-BOCS and PSQI subscales (except for the PSQI duration of sleep and the PSQI sleep disturbance). The PSQI sleep duration and the PSQI sleep disturbance subscales were not associated with the Y-BOCS, but these subscales were related to the BDI and the BAI scores.

Conclusion:

Sleep quality was found to be associated with disease severity, accompanying anxiety and depressive symptoms in OCD patients.

Keywords: Sleep, obsessive compulsive disorder, anxiety, depression

References

Öztürk MO, Uluşahin A. Ruh sağlığı ve bozuklukları. 11. Basım. Tuna Matbağcılık; 2008. 610-2 p.

Paterson JL, Reynolds AC, Ferguson SA, Dawson D. Sleep and obsessive-compulsive disorder (OCD). Sleep Med Rev 2013;17:465-74.

Yetkin S, Özgen F, Çelik C, Erdem M, Aydın H, Servisi DAHP. Obsesif kompulsif bozukluk hastalarında polisomnografi bulguları. Gülhane Tıp Derg 2009;51:94-6.

Bobdey M, Fineberg N, Gale TM, Patel A, Davies HA. Reported sleep patterns in obsessive compulsive disorder (OCD). Int J Psychiatry Clin Pract 2002;6:15-21.

Nicolas A. Sleep and quality of life in obsessive-compulsive disorder. Sleep Qual Life Clin Med 2008;291-7.

Goodman WK. The Yale-Brown Obsessive Compulsive Scale. Arch Gen Psychiatry 1989;46:1006.

Karamustafalıoğlu KO, Üçışık AM, Ulusoy M, Erkmen H. Yale-Brown obsesyon-kompulsiyon derecelendirme ölçeği’nin geçerlilik ve güvenilirlik çalışması. Bursa Savaş Ofset 1993;86.

Tek C, Uluğ B, Rezaki BG, Tanriverdi N, Mercan S, Demir B, Vargel S. Yale-Brown Obsessive Compulsive Scale and US National Institute of Mental Health Global Obsessive Compulsive Scale in Turkish: reliability and validity. Acta Psychiatr Scand 1995;91:410-3.

Beck AT, Ward CH, Mendelson M, Mock J, Erbaugh J. An inventory for measuring depression. Arch Gen Psychiatry 1961;4:561-71.

Kılınç S, Torun F. Türkiye’de Klinikte Kullanılan Depresyon Değerlendirme Ölçekleri. Dirim Tıp Gazetesi 2011;86:39-47.

Ulusoy M, Sahin N, Erkmen H. Turkish version of the Beck Anxiety Inventory: psychometric properties. J Cognitive Psychoter 1998;12:163-72.

Ağargün M, Kara H, Anlar Ö. Pittsburgh uyku kalitesi indeksinin geçerliği ve güvenirliği. Türk Psikiyatr Derg 1996;7:107-11.

Díaz-Román A, Perestelo-Pérez L, Buela-Casal G. Sleep in obsessive-compulsive disorder: A systematic review and meta-analysis. Sleep Med 2015;16:1049-55.

Insel TR, Gillin JC, Moore A, Mendelson WB, Loewenstein RJ, Murphy DL. The sleep of patients with obsessive-compulsive disorder. Arch Gen Psychiatry 1982;39:1372-7.

Hohagen F, Lis S, Krieger S, Winkelmann G, Riemann D, Fritsch-Montero R, Rey E, Aldenhoff J, Berger M. Sleep EEG of patients with obsessive-compulsive disorder. Eur Arch Psychiatry Clin Neurosci 1994;243:273-8.

Timpano KR, Carbonella JY, Bernert RA, Schmidt NB. Obsessive compulsive symptoms and sleep difficulties: Exploring the unique relationship between insomnia and obsessions. J Psychiatr Res 2014;57:101-7.

Donse L, Sack AT, Fitzgerald PB, Arns M. Sleep disturbances in obsessive-compulsive disorder: Association with non-response to repetitive transcranial magnetic stimulation (rTMS). J Anxiety Disord 2017;49:31-9.

Mukhopadhyay S, Fineberg NA, Drummond LM, Turner J, White S, Wulff K, Ghodse H. Delayed sleep phase in severe obsessive-compulsive disorder: A systematic case-report survey. CNS Spectr 2008;13:406-13.

Turner J, Drummond LM, Mukhopadhyay S, Ghodse H, White S, Pillay A, Fineberg NA. A prospective study of delayed sleep phase syndrome in patients with severe resistant obsessive-compulsive disorder. World Psychiatry 2007;6:108-11.

Robinson D, Walsleben J, Pollack S, Lerner G. Nocturnal polysomnography in obsessive-compulsive disorder. Psychiatry Res 1998;80:257-63.

Ramsawh HJ, Stein MB, Belik S-L, Jacobi F, Sareen J. Relationship of anxiety disorders, sleep quality, and functional impairment in a community sample. J Psychiatr Res 2009;43:926-33.

Voderholzer U, Riemann D, Huwig-Poppe C, Kuelz AK, Kordon A, Bruestle K, Berger M, Hohagen F. Sleep in obsessive compulsive disorder: Polysomnographic studies under baseline conditions and after experimentally induced serotonin deficiency. Eur Arch Psychiatry Clin Neurosci 2007;257:173-82.

Nordahl H, Havnen A, Havnen A, Hansen B, Hansen B, Öst LG, Kvale G. Predictors of sleep disturbances in treatment-seeking OCD-patients. Clin Neuropsychiatry 2014;11:182-6.

The Relation of Sleep Quality to Depression and Anxiety in Obsessive Compulsive Disorder

ABSTRACT

References