EN | TR
E-ISSN: 2757-850X
Determination and Comparison of Sleep Quality and Sleep Disorders in Patients with COPD According to GOLD Groups
PDF
Cite
Share
Request
Original Article
VOLUME: 10 ISSUE: 1
P: 42-47
March 2023

Determination and Comparison of Sleep Quality and Sleep Disorders in Patients with COPD According to GOLD Groups

J Turk Sleep Med 2023;10(1):42-47
DOI: 10.4274/jtsm.galenos.2022.28190
İlknur Kaya 1
Sibel Pekcan 2
Neşe Dursunoğlu 2
Hande Şenol 3
1. Kütahya Sağlık Bilimleri Üniversitesi Tıp Fakültesi, Göğüs Hastalıkları Anabilim Dalı, Kütahya, Türkiye
2. Pamukkale Üniversitesi Tıp Fakültesi, Göğüs Hastalıkları Anabilim Dalı, Denizli, Türkiye
3. Pamukkale Üniversitesi Tıp Fakültesi, Biyoistatistik Anabilim Dalı, Denizli, Türkiye
No information available.
No information available
Received Date: 27.03.2022
Accepted Date: 07.07.2022
Publish Date: 14.02.2023
PDF
Cite
Share
Request

ABSTRACT

Objective:

We evaluated and compare sleep quality and disorders according to the Global Initiative for Chronic Obstructive Lung Disease (GOLD) A, B, C, D groups in patients with Chronic Obstructive Pulmonary Disease (COPD) and to determine sleep disorders.

Materials and Methods:

Our study included 94 patients who applied to Pamukkale University Medical Faculty Hospital Chest Diseases Polyclinic between January 2016 and January 2017, were diagnosed with COPD according to GOLD criteria, were not in a COPD attack at the time of admission and agreed to participate in the study.

Results:

In patients with COPD, as the severity of stages increased, a decrease in mean FEV1 values was detected and as the FEV1 values decreased, the mean oxygen values measured during the night decreased. According to the GOLD stage, there was no significant difference between total sleep periods, sleep activity, sleep latency, rapid eye movement (REM) sleep duration, and non-REM sleep duration. According to polysomnography results, apnea-hypopnea index (AHI) was found to be below 5 in 40% of the patients. There was no statistically significant difference between the AHI and COPD stages (p=0.581).

Conclusion:

No significant difference was found between the COPD stage and AHI severity. However, as COPD stages increased, a decrease in mean nocturnal oxygen saturation was detected. Nocturnal oxygen desaturation is the main cause of comorbidities observed in patients COPD. As a result, careful attention should be given to night desaturation in advanced patients with COPD, and the necessary procedures must be performed to prevent comorbidities.

References

1
Global Strategy for the Diagnosis, Management and Prevention of COPD, Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2017. Available from: URL: http://goldcopd.org.
2
Casey KR, Cantillo KO, Brown LK. Sleep-related hypoventilation/hypoxemic syndromes. Chest 2007;131:1936-48.
3
Öztürk Ö. Chronic Obstructive Pulmonary Disease and Sleep. TÜSAD 2011;13:67-77.
4
Budhiraja R, Siddiqi TA, Quan SF. Sleep disorders in chronic obstructive pulmonary disease: etiology, impact, and management. J Clin Sleep Med 2015;11:259-70.
5
O’Donoghue FJ, Catcheside PG, Ellis EE, Grunstein RR, Pierce RJ, Rowland LS, Collins ER, Rochford SE, McEvoy RD; Australian trial of Noninvasive Ventilation in Chronic Airflow Limitation investigators. Sleep hypoventilation in hypercapnic chronic obstructive pulmonary disease: prevalence and associated factors. Eur Respir J 2003;21:977-84.
6
Hudgel DW, Martin RJ, Capehart M, Johnson B, Hill P. Contribution of hypoventilation to sleep oxygen desaturation in chronic obstructive pulmonary disease. J Appl Physiol Respir Environ Exerc Physiol 1983;55:669-77.
7
Fletcher EC, Scott D, Qian W, Luckett RA, Miller CC, Goodnight-White S. Evolution of nocturnal oxyhemoglobin desaturation in patients with chronic obstructive pulmonary disease and a daytime PaO2 above 60 mm Hg. Am Rev Respir Dis 1991;144:401-5.
8
Sergi M, Rizzi M, Andreoli A, Pecis M, Bruschi C, Fanfulla F. Are COPD patients with nocturnal REM sleep-related desaturations more prone to developing chronic respiratory failure requiring long-term oxygen therapy? Respiration 2002;69:117-22.
9
McNicholas WT. Chronic obstructive pulmonary disease and obstructive sleep apnea: overlaps in pathophysiology, systemic inflammation, and cardiovascular disease. Am J Respir Crit Care Med 2009;180:692-700.
10
Graham BL, Steenbruggen I, Miller MR, Barjaktarevic IZ, Cooper BG, Hall GL, Hallstrand TS, Kaminsky DA, McCarthy K, McCormack MC, Oropez CE, Rosenfeld M, Stanojevic S, Swanney MP, Thompson BR. Standardization of Spirometry 2019 Update. An Official American Thoracic Society and European Respiratory Society Technical Statement. Am J Respir Crit Care Med 2019;200:e70-e88.
11
Hoddes E, Zarcone V, Smythe H, Phillips R, Dement WC. Quantification of sleepiness: a new approach. Psychophysiology 1973;10:431-6.
12
Izci B, Ardic S, Firat H, Sahin A, Altinors M, Karacan I. Reliability and validity studies of the Turkish version of the Epworth Sleepiness Scale. Sleep Breath 2008;12:161-8.
13
Berry RB, Budhiraja R, Gottlieb DJ, Gozal D, Iber C, Kapur VK, Marcus CL, Mehra R, Parthasarathy S, Quan SF, Redline S, Strohl KP, Davidson Ward SL, Tangredi MM; American Academy of Sleep Medicine. Rules for scoring respiratory events in sleep: update of the 2007 AASM Manual for the Scoring of Sleep and Associated Events. Deliberations of the Sleep Apnea Definitions Task Force of the American Academy of Sleep Medicine. J Clin Sleep Med 2012;8:597-619.
14
İtil O, Köktürk O, Ardıç S, Çuhadaroğlu Ç, Fırat H. Uykuda Solunum Bozuklukları. Toraks Kitapları; 2019.
15
Lacasse Y, Sériès F, Vujovic-Zotovic N, Goldstein R, Bourbeau J, Lecours R, Aaron SD, Maltais F. Evaluating nocturnal oxygen desaturation in COPD--revised. Respir Med 2011 Sep;105:1331-7.
16
Lewis CA, Fergusson W, Eaton T, Zeng I, Kolbe J. Isolated nocturnal desaturation in COPD: prevalence and impact on quality of life and sleep. Thorax 2009;64:133-8.
17
De Angelis G, Sposato B, Mazzei L, Giocondi F, Sbrocca A, Propati A, Gentile J. Predictive indexes of nocturnal desaturation in COPD patients not treated with long term oxygen therapy. Eur Rev Med Pharmacol Sci 2001;5:173-9.
18
Mulloy E, McNicholas WT. Ventilation and gas exchange during sleep and exercise in severe COPD. Chest 1996;109:387-94.
19
Shackell BS, Jones RC, Harding G, Pearse S, Campbell J. ‘Am I going to see the next morning?’ A qualitative study of patients’ perspectives of sleep in COPD. Prim Care Respir J 2007;16:378-83.
20
Weitzenblum E, Chaouat A, Charpentier C, Ehrhart M, Kessler R, Schinkewitch P, Krieger J. Sleep-related hypoxemia in chronic obstructive pulmonary disease: causes consequences and treatment. Respiration 1997;64:187-93.
21
Levi-Valensi P, Weitzenblum E, Rida Z. Aubry P, Braghiroli A, Donner C, Aprill M, Zielinski J, Würtemberger G. Sleep- related oxygen desaturation and daytime pulmonary haemodynamics in COPD patients. Eur Respir J 1992;5:301-7.
22
Vukoja M, Kopitovic I, Milicic D, Maksimovic O, Pavlovic-Popovic Z, Ilic M. Sleep quality and daytime sleepiness in patients with COPD and astma. Clin Respir J 2018;12:398-403.
23
Berthon-Jones M, Sullivan CE. Ventilatory and arousal responses to hypoxia in sleeping humans. Am Rev Respir Dis 1982;125:632-9.
24
Sünnetçioğlu A, Karadaş S ,Özbay B, Sertoğullarından B. Prevalence of Obstructive Sleep Apnea Syndrome in Chronic Obstructive Pulmonary Disease. Abant Med J 2014;3:161-6.
25
Dehestani V, Rezaeetalab F, Amini M, Attaran D, Mohammadzadeh Lari Sh, Ghofraniha L. Determination of the Relationship between Severity of Obstructive Sleep Apnea and Chronic Obstructive Pulmonary Disease. J Cardiothorac Med 2017;5:530-2.
26
Soykök K, Arslan S, Demirel Y. Comorbidity Status in Chronic Obstructive Pulmonary Disease. İzmir Göğüs Hastanesi Dergisi 2017;3:145-55.